Holiday Inn Express & Suites St. Charles

Stay Your Way at the Holiday Inn Express and Suites in St. Charles, MO, Hotels. Located in the charming Historic St. Charles City, just 30 miles from downtown St. Louis and minutes from the confluence of the Missouri and Mississippi rivers. Our location, off Highway 370, just 4.5 miles from Historic St. Charles, is perfect for people traveling for business or pleasure. While St. Charles has history, charm, and attractions to entertain you for days, St. Louis is also a hotbed of activity. Our St. Charles hotel is not far from attractions like the St. Louis Zoo, the Baseball Cardinals Busch Stadium, Gateway Arch Riverfront, and more. Our St. Charles hotel is near the Ameristar and Hollywood Casinos if you wish to try your luck at the slots. When staying at our hotel in St. Charles, you have easy access to St. Louis, the St. Louis Airport, and several prominent business corridors. Our St. Charles hotel's 24-hour Business Center is equipped with a printer and PC, and our free high-speed Internet access keeps you efficiently connected. Our hotel in St. Charles is full of great amenities that everyone can enjoy. You can work up a sweat in the 24-hour Fitness Center, swim in the indoor pool, and indulge in a delicious complimentary, hot breakfast bar. Book a room today to take advantage of everything we offer.